Prodrugs of phosphonate nucoleotide analogues
US7803788B2 · kind B2 · utility
60Cited by
22References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2008 |
| Grant date | Sep 28, 2010 |
| Priority date | — |
| Expiry date | Nov 11, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5011
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A novel method has led to the identification of novel mixed ester-amidates of PMPA for retroviral or hepadnaviral therapy, including compounds of structure (5a)having substituent groups as defined herein. Compositions of these novel compounds in pharmaceutically acceptable excipients and their use in therapy and prophylaxis are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.