Patent · US Active

Novobiocin analogues as anticancer agents

US7811998B2 · kind B2 · utility

23Cited by

3References

18Claims

0Family size

Assignees

University of Kansas · US
The United States of America, as represented by the Department of Health and Human Services · US

Inventors

Brian S. J. Blagg · Lawrence, US
Len Neckers · Bethesda, US
Xiao YU · Maple Grove, US

Key dates

Filing date	Oct 1, 2009
Grant date	Oct 12, 2010
Priority date	—
Expiry date	Oct 1, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and neuroprotective agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.