Patent · US Active

Carboxyl- or hydroxyl-substituted benzimidazole derivatives

US7816540B2 · kind B2 · utility

0Cited by

0References

32Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Gregory Martin Benson · Therwil, CH
Konrad Bleicher · Glückstadt, DE
Uwe Grether · Weil am Rhein, DE
Bernd Kuhn · Sursee, CH
Rainer E. Martin · Basel, CH
Jean-Marc Plancher · Rixheim, FR
Hans Richter · Weil am Rhein, DE
Sven Taylor · Riedisheim, FR
Minmin Yang · Nanjing, CN

Key dates

Filing date	Dec 10, 2008
Grant date	Oct 19, 2010
Priority date	—
Expiry date	Dec 10, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to novel carboxyl- or hydroxyl-substituted benzimidazole derivatives of formula (I)wherein R1 to R6 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.