Benzylic glycoside derivatives and methods of use

US7838498B2 · kind B2 · utility

Assignee

• Theracos, Inc. · US

Inventors

• Yuanwei Chen · Sichuan, CN
• Yan Feng · Chengdu, CN
• Baihua Xu · Shanghai, CN
• Binhua Lv · 安丰镇, CN
• Brian Seed · Boston, US
• Michael J. Hadd · San Diego, US
• Huawei Cheng · Shanghai, CN
• Zelin Sheng · Montgomery, US
• Min Xu · Lo Wu, CN
• Congna Wang · Pudong New District, CN
• Jiyan Du · Shanghai, CN
• Lili Zhang · Colonia, US
• Ge Xu · Columbia, US
• Yuelin Wu · Beijing, CN

Key dates

• Filing date: Apr 1, 2008
• Grant date: Nov 23, 2010
• Expiry date: Jan 30, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.