Optically active carbamates, process for preparation thereof and use thereof as pharmaceutical intermediates
US7851627B2 · kind B2 · utility
2Cited by
3References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 2006 |
| Grant date | Dec 14, 2010 |
| Priority date | — |
| Expiry date | Aug 8, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/185
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is related to 1-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation of 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers and salts thereof. 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers thereof are important intermediates in the preparation of non-sedating antihistamine-type active pharmaceutical ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.