Compounds

US7855213B2 · kind B2 · utility

Assignees

• ASTRAZENECA AB · SE
• ASTEX THERAPEUTICS LIMITED · GB

Inventors

• James Arnold · West Chester, US
• Phil Edwards · Wilmington, US
• Mark Sylvester · Waltham, US
• Stefan Berg · Ekerö, SE
• Jörg Holenz · Munkfors, SE
• Annika Kers · Malung, SE
• Karin Kolmodin · Grafton, GB
• Laszlo Rakos · Malung, SE
• Liselotte Ohberg · Malung, SE
• Rotticci Didier · Malung, SE
• Gianni Chessari · Cambridge, GB
• Miles Stuart Congreve · Cambridge, GB
• Christopher William Murray · Cambridge, GB
• Sahil Patel · Cambridge, GB

Key dates

• Filing date: Jun 13, 2007
• Grant date: Dec 21, 2010
• Expiry date: Nov 15, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to novel compounds having the structural formula I below:and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.