Methods for inhibiting angiogenesis with inhibitors of proadrenomedullin N-terminal 20 peptide (PAMP)

US7862815B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Frank Cuttitta · Adamstown, US
• Alfredo Martinez · Chihuahua, MX
• William G. Stetler-Stevenson · Kensington, US

Key dates

• Filing date: Sep 29, 2008
• Grant date: Jan 4, 2011
• Expiry date: Sep 29, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure concerns the use of peptides and compositions, such as pharmaceutical compositions, to influence angiogenesis. Particular methods are useful for promoting angiogenesis, while others are particularly useful for inhibiting angiogenesis.