Method of determining chymase activity with secretory leukocyte protease inhibitor
US7892779B2 · kind B2 · utility
2Cited by
9References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 2009 |
| Grant date | Feb 22, 2011 |
| Priority date | — |
| Expiry date | Jul 9, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/811
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
It is now discovered that human chymase cleaves human SLPI at a specific site and that this cleavage can be used as an indicator of chymase activity. The present invention provides methods of diagnosing a chymase-associated disease or evaluating the efficiency of a treatment of a chymase-associated disease in a human subject by measuring SLPI processing, as well as other related methods and compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.