Patent · US Active

Aza-benzothiophenyl compounds and methods of use

US7893085B2 · kind B2 · utility

6Cited by
13References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 20, 2007
Grant dateFeb 22, 2011
Priority date
Expiry dateAug 20, 2027

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to azabenzothiophenyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to azabenzothiophenyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.