Piperazinyl pyrimidine derivatives
US7902184B2 · kind B2 · utility
7Cited by
8References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 21, 2007 |
| Grant date | Mar 8, 2011 |
| Priority date | — |
| Expiry date | Jul 19, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula I and their pharmaceutically acceptable salts wherein formula I is:wherein X, Y, Z, R1 and R2 are as defined in the description and claims. The compounds of the present invention act as antagonists and/or inverse agonists at the histamine 3 receptor and are useful for the treatment and/or prevention of diseases such as obesity, metabolic syndrome (syndrome X), and other eating disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.