Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them

US7902379B2 · kind B2 · utility

Assignee

• Abbott GmbH & Co. KG · DE

Inventors

• Wilfried Lubisch · Mannheim, DE
• Wilfried Hornberger · Wiesbaden, DE
• Thorsten Oost · Biberach an der Riß, DE
• Daryl Sauer · Pleasant Prairie, US
• Liliane Unger · Ludwigshafen, DE
• Wolfgang Wernet · Ludwigshafen, DE
• Hervé Geneste · Schifferstadt, DE

Key dates

• Filing date: Sep 30, 2004
• Grant date: Mar 8, 2011
• Expiry date: Nov 20, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R3, R4, R5 R6 and R7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivatives can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.