CETP inhibitors
US7910592B2 · kind B2 · utility
10Cited by
5References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 2006 |
| Grant date | Mar 22, 2011 |
| Priority date | — |
| Expiry date | Dec 29, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), B is a cyclic group other than phenyl, and B has a cyclic substituent at a position that is ortho to the position at which B is connected to the remainder of the structure of Formula (I). The 5-membered ring of Formula (I) has a second cyclic substituent in addition to B.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.