5-anilinoimidazo[1,5-a]-pyridines inhibitors of MEK kinase
US7923456B2 · kind B2 · utility
1Cited by
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17Claims
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Assignee
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Key dates
| Filing date | Apr 29, 2009 |
| Grant date | Apr 12, 2011 |
| Priority date | — |
| Expiry date | Apr 30, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to imidazopyridines of formula I with anti-cancer and/or anti-inflammatory activity and more specifically to imidazopyridines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.