Patent · US Active

Aza-pyridopyrimidinone derivatives

US7928106B2 · kind B2 · utility

4Cited by

1References

17Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Aurelia Conte · Basel, CH
Henrietta Dehmlow · Weil am Rhein, DE
Uwe Grether · Weil am Rhein, DE
Nicole A. Kratochwil · Sool, CH
Holger Kuehne · Soest, DE
Robert Narquizian · La Valette-du-Var, FR
Constantinos G. Panousis · Bottmingen, CH
Jens-Uwe Peters · Weil am Rhein, DE
Fabienne Ricklin · Hombourg, FR

Key dates

Filing date	Mar 17, 2008
Grant date	Apr 19, 2011
Priority date	—
Expiry date	May 10, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D475/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention is concerned with novel aza-pyridopyrimidinone derivatives of formula (I):wherein R1, R2, R3, R4, R5, X1, X2, X3, Y, Z, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds are HM74A agonists and can be used in treating or preventing diseases which are modulated by HM74A agonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.