Process for preparing an intermediate to opioid receptor antagonists
US7932402B2 · kind B2 · utility
8Cited by
2References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 15, 2008 |
| Grant date | Apr 26, 2011 |
| Priority date | — |
| Expiry date | Jul 8, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides an efficient method for preparing 3-endo-(8-azabicyclo[3.2.1]oct-3-yl)benzamide by hydrogenation, under controlled conditions, of an amino-protected 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)benzamide intermediate in which the amino-protecting group is removable by catalytic hydrogenation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.