Patent · US Active

Fermentation process using specific oxygen uptake rates as a process control

US7939298B2 · kind B2 · utility

1Cited by

0References

5Claims

0Family size

Assignee

CARGILL, INCORPORATED · US

Inventors

Pim Van Hoek · Minnetonka, US
Aristos Aristidou · Highlands Ranch, US
Brian J. Rush · Minneapolis, US

Key dates

Filing date	Feb 14, 2007
Grant date	May 10, 2011
Priority date	—
Expiry date	Nov 1, 2029

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/52
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.