Patent · US Active

Isoxazolo-pyridazine derivatives

US7943619B2 · kind B2 · utility

1Cited by

1References

15Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Bernd Buettelmann · Palo Alto, US
Roland Jakob-Roetne · Inzlingen, DE
Henner Knust · Rheinfelden (Baden), DE
Andrew Thomas · Birsfelden, CH

Key dates

Filing date	Nov 25, 2008
Grant date	May 17, 2011
Priority date	—
Expiry date	Jul 16, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to isoxazolo-pyridazine compounds, in particular those of formula I as described above and to a pharmaceutically acceptable salts thereof, having affinity and selectivity for the GABA A α5 receptor binding site, their manufacture, pharmaceutical compositions containing them and their use as cognitive enhancers or for the treatment of cognitive disorders like Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.