Wnt antagonists and their use in the diagnosis and treatment of Wnt-mediated disorders
US7947277B2 · kind B2 · utility
23Cited by
5References
13Claims
0Family size
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Key dates
| Filing date | Sep 7, 2007 |
| Grant date | May 24, 2011 |
| Priority date | — |
| Expiry date | Sep 7, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides for chimeric Wnt antagonists comprising a Frz domain component derived from a Frizzled protein, a secreted Frizzled related protein or Ror protein and an Fc immunoglobulin component, and their use in the treatment and diagnostic detection of cellular Wnt signaling and Wnt-mediated disorders, including cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.