HIV vaccines based on Env of multiple clades of HIV

US7947822B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Gary J. Nabel · Cambridge, US
• Bimal Chakrabarti · Gaithersburg, US
• Wing-Pui Kong · Germantown, US
• Yue Huang · Bethesda, US
• Zhi-yong Yang · Potomac, US

Key dates

• Filing date: Jan 7, 2010
• Grant date: May 24, 2011
• Expiry date: Jan 7, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16234
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a composition comprising a pharmaceutically acceptable carrier and six plasmids, each of which encodes an HIV Env, Gag, Pol, or Nef protein. The invention also provides a method of inducing an immune response in an animal using the composition.