Patent · US Active

Certain substituted amides, method of making, and method of use thereof

US7947835B2 · kind B2 · utility

14Cited by
1References
67Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 9, 2006
Grant dateMay 24, 2011
Priority date
Expiry dateMay 19, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

At least one chemical entity chosen from compounds of Formula 2and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, and mixtures thereof is described herein.Pharmaceutical compositions comprising at least one chemical entity of the invention, together with at least one pharmaceutically acceptable vehicle chosen from carriers adjuvants, and excipients, are described.Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.