Certain substituted amides, method of making, and method of use thereof
US7947835B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 9, 2006 |
| Grant date | May 24, 2011 |
| Priority date | — |
| Expiry date | May 19, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
At least one chemical entity chosen from compounds of Formula 2and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, and mixtures thereof is described herein.Pharmaceutical compositions comprising at least one chemical entity of the invention, together with at least one pharmaceutically acceptable vehicle chosen from carriers adjuvants, and excipients, are described.Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.