Patent · US Active

Constrained spirocyclic compounds as CGRP receptor antagonists

US7951795B2 · kind B2 · utility

43Cited by
6References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 2007
Grant dateMay 31, 2011
Priority date
Expiry dateMar 21, 2028

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of formula I:(wherein variables A1, A2, A3, G1, G2, G3, J, m, n, p, R1, R2, R3, R4 and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.