Patent · US Active

Modulators of ATP-binding cassette transporters

US7973038B2 · kind B2 · utility

103Cited by

4References

45Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

Sara S. Hadida Ruah · Village of La Jolla, US
Matthew Hamilton · Hackettstown, US
Mark Miller · San Diego, US
Peter D.J. Grootenhuis · San Diego, US
Brian Bear · Oceanside, US
Jason McCartney · Encinitas, US
Jinglan Zhou · San Diego, US

Key dates

Filing date	Apr 28, 2010
Grant date	Jul 5, 2011
Priority date	—
Expiry date	Apr 28, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.