Patent · US Active

Method for detecting a mutation in a repetitive nucleic acid sequence

US7977108B2 · kind B2 · utility

11Cited by

6References

2Claims

0Family size

Assignee

Roche Molecular Systems, Inc. · US

Inventors

Christopher Newhouse · Carmel, US
Stephen G. Will · Oakland, US
Amar Gupta · Danville, US

Key dates

Filing date	Jul 13, 2006
Grant date	Jul 12, 2011
Priority date	—
Expiry date	Jul 11, 2027

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/143333
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides methods and probe nucleic acids for detecting mutant forms of target nucleic acids that comprise repetitive nucleotide sequences. In certain embodiments, for example, these approaches and reagents can be used to detect instability in regions of genomic DNA that include microsatellite markers. The invention also provides related reaction mixtures, systems, and kits.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.