Patent · US Active

HPRP4s modifiers of the p53 pathway and methods of use

US7993829B2 · kind B2 · utility

2Cited by

1References

10Claims

0Family size

Assignee

Exelixis, Inc. · US

Inventors

Lori Friedman · Redwood City, US
Gregory D. Plowman · Seattle, US
Tak Hung · Foster City, US
Helen Francis-Lang · San Francisco, US
Danix Li · Zionsville, US
Roel Funke · South San Francisco, US
Michael Costa · San Francisco, US

Key dates

Filing date	Jan 26, 2007
Grant date	Aug 9, 2011
Priority date	—
Expiry date	Jan 26, 2027

Classification

Technology area (CPC G)Physics
CPC primaryG01N2510/00
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.