Azonafide derived tumor and cancer targeting compounds

US8008316B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Nadya I. Tarasova · Frederick, US
• Marcin Dyba · Frederick, US
• Christopher J. Michejda · North Potomac, US

Key dates

• Filing date: Sep 12, 2007
• Grant date: Aug 30, 2011
• Expiry date: Jun 14, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

An azonafide-based compound of Formula I, a composition comprising the compound, and a method of using the compound to deliver a cytotoxic azonafide derivative to a cell, as well as related compounds and methods for the use thereof to pre-pare an azonafide-based compound of Formula I.