Patent · US Active

Imidazopyridines

US8017604B2 · kind B2 · utility

2Cited by

1References

29Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Daniela Alberati · Zofingen, CH
Rubén Alvarez Sánchez · Rixheim, FR
Konrad Bleicher · Glückstadt, DE
Alexander Flohr · Basel, CH
Katrin Groebke Zbinden · Liestal, CH
Matthias Koerner · Antdorf, DE
Bernd Kuhn · Sursee, CH
Jens-Uwe Peters · Weil am Rhein, DE
Markus Rudolph · Basel, CH

Key dates

Filing date	Sep 21, 2010
Grant date	Sep 13, 2011
Priority date	—
Expiry date	Sep 21, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention is concerned with novel imidazopyridine derivatives of formula (I)wherein R1, R2, R3, R4, R5 and A are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used for the treatment of various diseases, including central nervous system disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.