N-substituted-pyrrolidines as inhibitors of MDM2-P-53 interactions
US8017607B2 · kind B2 · utility
22Cited by
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13Claims
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Key dates
| Filing date | Oct 6, 2010 |
| Grant date | Sep 13, 2011 |
| Priority date | — |
| Expiry date | Oct 6, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are provided compounds of the formulawherein X, Y, R1, R2, R3, R3, R4, and R5 are as described hereinand enantiomers and pharmaceutically acceptable salts and esters thereof which are useful as anticancer agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.