6-modified bicyclic nucleic acid analogs
US8022193B2 · kind B2 · utility
125Cited by
114References
19Claims
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Key dates
| Filing date | May 5, 2010 |
| Grant date | Sep 20, 2011 |
| Priority date | — |
| Expiry date | May 5, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.