Patent · US Active

Optimized Fc variants and methods for their generation

US8039592B2 · kind B2 · utility

57Cited by

49References

19Claims

0Family size

Assignee

Xencor, Inc. · US

Inventors

Gregory Alan Lazar · Los Angeles, US
Arthur J. Chirino · Camarillo, US
Wei Dang · Pasadena, US
John Desjarlais · Pasadena, US
Stephen K. Doberstein · San Francisco, US
Robert Hayes · Paoli, US
Sher Bahadur Karki · Pasadena, US
Omid Vafa · Monrovia, US

Key dates

Filing date	Oct 31, 2007
Grant date	Oct 18, 2011
Priority date	—
Expiry date	May 17, 2029

Classification

Technology area (CPC G)Physics
CPC primaryG16B15/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.