Substituted pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors of phospatidylinositol 3-kinase alpha

US8044062B2 · kind B2 · utility

Assignee

• Exelixis, Inc. · US

Inventors

• Tae-Gon Baik · Seoul, KR
• Chris A. Buhr · Daly City, US
• Katherine Lara · San Mateo, US
• Sunghoon Ma · Foster City, US
• Morrison B. Mac · San Francisco, US
• John M. Nuss · Danville, US
• Longcheng Wang · Palo Alto, US
• Yong Wang · South San Francisco, US
• Bryan K. S. Yeung · Filiates, GR

Key dates

• Filing date: Oct 9, 2006
• Grant date: Oct 25, 2011
• Expiry date: Jan 20, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is directed to Compounds of Formula I:and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.