Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same
US8053477B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Mar 27, 2003 |
| Grant date | Nov 8, 2011 |
| Priority date | — |
| Expiry date | Feb 9, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds that bind S100 and inhibit the S100-p53 protein-protein interaction and activate the tumor suppressor activity of p53, and thus which have an antineoplastic effect are disclosed, as well as methods for identifying these compounds, compositions comprising the same, and methods of using the same to treat cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.