MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use
US8067180B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Nov 24, 2003 |
| Grant date | Nov 29, 2011 |
| Priority date | — |
| Expiry date | Feb 10, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with defective Rac, axin, and beta-catenin function. Methods for identifying modulators of Rac, axin, and beta-catenin, comprising screening for agents that modulate the activity of MAPK are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.