Patent · US Active

Stable recombinant adenosine deaminase

US8071741B2 · kind B2 · utility

4Cited by

35References

19Claims

0Family size

Assignee

Defiante Farmaceutica, S.A. · PT

Inventors

David Filpula · Gaithersburg, US
Stephen Kenneth Youngster · Piscataway, US

Key dates

Filing date	Apr 18, 2008
Grant date	Dec 6, 2011
Priority date	—
Expiry date	Jun 3, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A mutein recombinant adenosine deaminase having any oxidizable cysteine residue replaced by a non-oxidizable amino acid residue is disclosed. Stabilized recombinant adenosine deaminase, polymer conjugates and methods of treatment using the same are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.