Inventor · Gaithersburg, MD, US

David Filpula

28Patents
17h-index
18Co-inventors
74Inventor score

Filing activity: May 30, 1990 → Apr 18, 2008

Most-cited inventions

PatentTitleAreaCited byStatus
US5869620A Multivalent antigen-binding proteins Chemistry; Metallurgy 109 Expired
US5856456A Linker for linked fusion polypeptides Emerging Cross-Sectional Technologies 88 Expired
US5990275A Linker and linked fusion polypeptides Emerging Cross-Sectional Technologies 64 Expired
US6743896B2 Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof Chemistry; Metallurgy 55 Expired
US5767260A Antigen-binding fusion proteins Chemistry; Metallurgy 55 Expired
US5763733A Antigen-binding fusion proteins Chemistry; Metallurgy 48 Expired
US5049504A Bioadhesive coding sequences Chemistry; Metallurgy 38 Expired
US6872393B2 Polyalkylene oxide-modified single chain polypeptides Chemistry; Metallurgy 37 Expired
US6743908B2 Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof Chemistry; Metallurgy 37 Expired
US6121424A Multivalent antigen-binding proteins Chemistry; Metallurgy 34 Expired
US6515110B1 Multivalent antigen-binding proteins Chemistry; Metallurgy 33 Expired
US6333396A Method for targeted delivery of nucleic acids Chemistry; Metallurgy 30 Expired
US5202256A Bioadhesive precursor protein expression vectors Chemistry; Metallurgy 26 Expired
US6103889A Nucleic acid molecules encoding single-chain antigen-binding proteins Chemistry; Metallurgy 26 Expired
US6025165A Methods for producing multivalent antigen-binding proteins Chemistry; Metallurgy 25 Expired
US6323322A Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof Chemistry; Metallurgy 20 Expired
US6027725A Multivalent antigen-binding proteins Chemistry; Metallurgy 20 Expired
US6824782B2 Polyalkylene oxide-modified single chain polypeptides Chemistry; Metallurgy 17 Expired
US5804183A Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same Chemistry; Metallurgy 14 Expired
US7150872B2 Polyalkylene oxide-modified single chain polypeptides Chemistry; Metallurgy 12 Expired
US7632504B2 Polyalkylene oxide-modified single chain polypeptides Chemistry; Metallurgy 9 Expired
US5916793A Arginine deiminase derived from Mycoplasma arthritidis and polymer conjugates containing the same Chemistry; Metallurgy 9 Expired
US8741283B2 Adenosine deaminase anticancer therapy Chemistry; Metallurgy 6 Active
US7807436B2 Recombinant host for producing L-asparaginase II Emerging Cross-Sectional Technologies 5 Active
US8071741B2 Stable recombinant adenosine deaminase Human Necessities 4 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.