Patent · US Active

3,3′-spiroindolinone derivatives

US8076482B2 · kind B2 · utility

26Cited by

4References

4Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Li Chen · Shanghai, CN
Xingchun Han · Shanghai, CN
Song Yang · Shanghai, CN
Zhuming Zhang · Fryeburg, US

Key dates

Filing date	Mar 29, 2010
Grant date	Dec 13, 2011
Priority date	—
Expiry date	Mar 29, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

There are provided compounds of the formulaor a pharmaceutically acceptable salt or ester thereof wherein X, Y, W, W′, V, V′, V″, R1, R2 and R3 are as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.