Integrated system and method for multichannel neuronal recording with spike/LFP separation, integrated A/D conversion and threshold detection
US8090674B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 6, 2005 |
| Grant date | Jan 3, 2012 |
| Priority date | — |
| Expiry date | Jul 18, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06F2218/14
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A CMOS integrated circuit for multi-channel neuronal recording with twelve true-differential channels, band separation and digital offset calibration. The recorded signal is separated into 2 bands: a low-frequency, local field potential (LFP); and high-frequency spike data. Digitally programmable gains for the LFP and spike bands are provided. A mixed-signal front-end processor for multi-channel neuronal recording is also described. It receives twelve differential-input channels of implanted recording electrodes. A programmable cutoff HPF blocks DC and low frequency input drift at about 1 Hz. The signals are band-split at about 200 Hz to low-frequency local field potential (LFP) and high-frequency spike data (SPK), which is band limited by a programmable-cutoff LPF. The analog signals are converted into digital form, and streamed out over a serial digital bus at up to 8 Mbps. A special interface system incorporating an embedded CPU core in a programmable logic device accompanied by real-time software allows connectivity to a computer host.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.