Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8
US8106173B2 · kind B2 · utility
7Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 2007 |
| Grant date | Jan 31, 2012 |
| Priority date | — |
| Expiry date | Apr 6, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/336
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.