Polypeptoid pulmonary surfactants
US8114830B2 · kind B2 · utility
5Cited by
2References
7Claims
0Family size
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Inventors
Key dates
| Filing date | May 2, 2005 |
| Grant date | Feb 14, 2012 |
| Priority date | — |
| Expiry date | Oct 24, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides spreading agents based on sequence-specific oligomers comprising a peptoid, a peptide-peptoid chimera, a retropeptoid or a retro(peptoid-peptide) chimera, and methods for using the same, including for the treatment of respiratory distress of the lungs. The spreading agents are sequence-specific oligomers, including retrosequence-specific oligomers, based on a peptide backbone, that are designed as analogs of surfactant protein-B or surfactant protein-C.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.