Methods of using sIP-10, CD26 inhibitors and CXCR3 levels in a sample to assess clearance of infection, response to interferon therapy, and treating chronic infections
US8124332B2 · kind B2 · utility
2Cited by
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10Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 31, 2009 |
| Grant date | Feb 28, 2012 |
| Priority date | — |
| Expiry date | Jul 31, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for the treatment of infection, a disease, or a condition using CD26 (DPIV) inhibitors. The present invention also relates to an antibody that binds to the IP-10 protein and a method of monitoring the necessity for administering a CD26 inhibitor to a patient, comprising evaluating a level of sIP-10, a activity of CD26, and/or a level of CXCR3 cells in a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.