Patent · US Active

Optimized Fc variants and methods for their generation

US8124731B2 · kind B2 · utility

50Cited by

49References

4Claims

0Family size

Assignee

Xencor, Inc. · US

Inventors

Gregory Alan Lazar · Los Angeles, US
Arthur J. Chirino · Camarillo, US
Wei Dang · Pasadena, US
John Desjarlais · Pasadena, US
Stephen K. Doberstein · San Francisco, US
Robert Hayes · Paoli, US
Sher Bahadur Karki · Pasadena, US
Omid Vafa · Monrovia, US

Key dates

Filing date	Oct 29, 2007
Grant date	Feb 28, 2012
Priority date	—
Expiry date	Oct 31, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.