Compositions and methods for inhibiting expression of the MYC gene
US8124752B2 · kind B2 · utility
32Cited by
0References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 2007 |
| Grant date | Feb 28, 2012 |
| Priority date | — |
| Expiry date | Aug 20, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/322
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the MYC gene (MYC gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the MYC gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by MYC gene expression and the expression of the MYC gene using the pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.