Chemical compound and its use

US8124775B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Hilmar Bischoff · Wuppertal, DE
• Heike Gielen-Haertwig · Monheim, DE
• Volkhart Min-Jian Li · Velbert, DE
• Carsten Schmeck · Wuppertal, DE
• Michael Thutewohl · Buchs, CH
• Alexandros Vakalopoulos · Hilden, DE
• Olaf Weber · Wülfrath, DE
• Martina Wuttke · Wuppertal, DE

Key dates

• Filing date: Dec 15, 2005
• Grant date: Feb 28, 2012
• Expiry date: Jan 4, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.