Substituted benzene compounds as modulators of the glucocorticoid receptor
US8138189B2 · kind B2 · utility
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45Claims
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Key dates
| Filing date | Mar 19, 2010 |
| Grant date | Mar 20, 2012 |
| Priority date | — |
| Expiry date | Mar 19, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula Iwherein R.sup.1a to R.sup.1e and R.sup.2 to R.sup.5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.