Glucocorticoid receptor antagonists
US8143280B2 · kind B2 · utility
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13Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 15, 2008 |
| Grant date | Mar 27, 2012 |
| Priority date | — |
| Expiry date | Nov 5, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula Iwherein A, n, R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.