Patent · US Active

Trisubstituted 1,2,4-triazoles

US8143419B2 · kind B2 · utility

4Cited by

0References

11Claims

0Family size

Assignee

Janssen Pharmaceutica NA · BE

Inventors

Johannes Wilhelmus John F. Thuring · Ekeren, BE
Gregor James MacDonald · Zoersel, BE
Anne Simone Josephine Lesage · Zoersel, BE
Wei Zhuang · Monheim, DE
Marcel Frans Leopold De Bruyn · Wortel, BE
Frans Alfons Maria Van den Keybus · Beerse, BE
Yves Emiel Maria Van Roosbroeck · Heist-op-den-Berg, BE
Theodorus Dinklo · Beerse, BE
James E. Duffy · Cambridge, GB

Key dates

Filing date	Apr 19, 2007
Grant date	Mar 27, 2012
Priority date	—
Expiry date	Jul 3, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/048
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to 3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.