Patent · US Active

Marks as modifiers of the p53 pathway and methods of use

US8153384B2 · kind B2 · utility

0Cited by

2References

15Claims

0Family size

Assignee

Exelixis, Inc. · US

Inventors

Lori Friedman · Redwood City, US
Gregory D. Plowman · Seattle, US
Helen Francis-Lang · San Francisco, US
Danxi Li · Skillman, US
Roel Funke · South San Francisco, US
Marcia Belvin · South San Francisco, US
Mario N. Lioubin · Bellevue, US

Key dates

Filing date	Jun 10, 2010
Grant date	Apr 10, 2012
Priority date	—
Expiry date	Jun 10, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N2510/00
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Human MARK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of MARK are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.