Pseudoproline dipeptides
US8153815B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Sep 25, 2009 |
| Grant date | Apr 10, 2012 |
| Priority date | — |
| Expiry date | Jun 23, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a process for the manufacture of pseudo proline dipeptides of the formulawherein R1 is a side chain of an alpha amino acid, R2 is an amino protecting group and R3 and R4 are independently selected from hydrogen or C1-4-alkyl, R5 is hydrogen or methyl starting from an amino acid derivative of the formulawherein R1 and R2 are as above.Pseudo proline dipeptides can be used as reversible protecting groups for Ser, Thr and Cys and thus are versatile tools in peptide chemistry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.