Patent · US Active

Immunostimulatory nucleic acid molecules

US8158592B2 · kind B2 · utility

17Cited by

167References

10Claims

0Family size

Assignees

COLEY PHARMACEUTICAL GMBH · DE
The United States of America, as represented by the Department of Health and Human Services · US
University of Iowa Research Foundation · US

Inventors

Arthur M. Krieg · Wellesley, US
Joel Kline · Iowa City, US
Dennis Klinman · Potomac, US
Alfred Steinberg · Potomac, US

Key dates

Filing date	Jan 7, 2005
Grant date	Apr 17, 2012
Priority date	—
Expiry date	Jan 14, 2028

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.