PD-1 binding proteins
US8168757B2 · kind B2 · utility
319Cited by
3References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 3, 2009 |
| Grant date | May 1, 2012 |
| Priority date | — |
| Expiry date | Mar 3, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention features PD-1 binding proteins, a subset of which inhibits binding of PD-L1 to the PD-1 receptor. These binding proteins can be employed to modulate the immune system through the manipulation of the PD-1 signaling pathway, enhancing host immunity to treat infections and cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.