Tie-2 modulators and methods of use
US8178570B2 · kind B2 · utility
3Cited by
3References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 8, 2004 |
| Grant date | May 15, 2012 |
| Priority date | — |
| Expiry date | Jul 26, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Tie-2. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.